How long does Suboxone Withdrawal Last?
This is the number one question asked and in simple terms– it lasts a pretty long time and it sucks really bad.
Now for some real medical explanation about the length of Suboxone Withdrawal. First of all, Buprenorphine’s duration of action is not dependent on the serum halflife. It is highly protein bound a actnd primarily hepatically metabolized (CYP 3A4). The agent is subject to extensive first pass metabolism. Buprenorphine undergoes Ndealkylation to norbuprenorphine and glucoronidation. Norbuprenorphine is an active metabolite, which has little efficacy but is a potent respiratory depressant.
So what does this mean? It means that Suboxone undergoes changes as your liver metabolizes is, and each resultant metabolite has specific actions and lengths of duration. The long half-life of Suboxone is a good and bad thing, it is good because the Suboxone takes a long time to be filtered from your body. But the long half-life can make withdrawals very long, and from personal experience I can say that it is relatively severe, not as severe as withdrawal from oxycontin or heroin, but annoyingly long lasting. The other negative of the way Suboxone is metabolized is that it turns into different substances that themselves have a duration of action and can contribute to withdrawal symptoms.
From experience, and talking with others I have learned that the best way to minimize withdrawal symptoms is a very, very slow and very very gradual taper. You can use the Suboxone Taper Charting Tool on this site to build your own taper schedule and see if your doctor is willing to let you follow it. You should never adjust your medication without doctor approval.
Drug Abuse and Dependence:
Buprenorphine can cause physical dependence with continuous administration. Individuals may experience withdrawal symptoms upon
abrupt discontinuation. However, the effects are usually milder than what is experienced with a full opioid agonist.
Side effects of buprenorphine are similar to those of other opioids.
- sleep difficulties
- flu-like symptoms.
Buprenorphine can precipitate an opioid withdrawal syndrome.
Signs and symptoms of opioid withdrawal include:
- dysphoric mood
- GI distress (nausea, vomiting, diarrhea)
- pupillary dilation
- mild fever
- Respiratory depression, which can potentially result in death.
- Most of the fatal cases occurred in combination with other CNS depressants such as alcohol or benzodiazepines.
Stories about Suboxone Withdrawal – One I respectfully disagree with
References:Suboxone takes about 2-5 days for the worst part of the symptoms to go away, and a couple weeks for mild symptoms to deminish. It kinda sucks cuz I’m actually goin through it right now. Today is my third day and i decided to snort about .25 mg to take away the chills. Its not that bad though, I’ve definetly been through allot worse having been through withdrawls from herion, cocaine, and alchahol. Not all at once of course, I’ve taken each one to the limit many times in the past 4 years. Pretty crazy sein how I’m only 18 yrs. old. I swear i know almost everything about drugs. And trust me i know that’s not cool at all. I really hate drugs, they just seem to like me allot for some reason. but ya my fingers hurt so i hope i was a little bit of help. If you have any other questions about suboxone or ne thing else feel free to ask. Peace.
I have been on suboxone for 2 yrs and recently went off it. I quit it on a Monday, and didn’t notice anything for a few days, then the withdrawls kicked in. I was depressed, with diarreah, and cold and hot sweats and an overall feeling of pure exaustion. It’s been a little over a week now and I’m slowly feeling better each day. I still can’t stay asleep though. I thought the suboxone was a wonderful drug to get me off my lortab addiction, but they always told me there wouldn’t be any withdrawl with the suboxone. They lied.
IV,E COME OFF SUBUTEX COLD TURKEY THEN SUBOXONE YEARS LATER BY TAPERING.COLD TURKEY IS TERRIBLE AND IT TAKES 2 DAYS BEFORE YOU EVEN START TO W/D.THE WORST OF IT LASTS TIL ABOUT 10 TO 12 DAYS BUT YOU STILL CANT SLEEP RIGHT AND GET RESTLESS FOR AROUND SIX WEEKS AFTER QUITING.IF YOU TAPER ITS A LOT EASIER BUT YOU,VE GOT TO SLOW IT RIGHT RIGHT DOWN WHEN YOU GO UNDER 2MG.IF YOU TAKE YOUR TIME UNDER 2MG,AND ARE PREPARED TO DRAG IT OUT,THEN YOU WILL TAPER OFF IT A LOT EASIER.YES.YOU WILL STILL HAVE W/D SYMPTOMS BUT THEY WONT BE NEAR AS BAD AS GOING COLD TURKEY.BUPRENORPHINE W/D IS NOT AS BAD AS METHADONE W/D COLD TURKEY AS IV,E COME OFF THAT TOO.Read more: http://wiki.answers.com/Q/How_long_will_withdrawal_symptoms_from_suboxone_last#ixzz1y1cmBfqX
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