Zubsolv, A New Formulation of Buprenorphine and Naloxone
Zubsolv is a new drug formulation of Buprenorphine and Naloxone. Zubsolv is similar to Suboxone and has been approved by the FDA for the same use, opiate addiction.
- ZUBSOLV is available in 2 doses for Opioid Dependence, 5.7 mg and 1.4 mg.
- ZUBSOLV is Individually sealed in the highest level of child-resistant unit-dose blister packs (F1 child-resistant)
Zubsolv v.s. Suboxone for Opiate Dependence
Zubsolv comes in two dose sizes that compete directly with Suboxone’s 8mg/2mg and 4mg/1mg strips and sublingual tablets. Orexo, the maker of Zubsolv claims that the dose formulations are comparable to Suboxone even though they contain lower amounts of Buprenorphine and Naloxone. The lower dose sizes are equivalent because the new drug formulation has a higher bio-availability, meaning that a higher percentage of the dose is available to the human body in this new formulation.
The jury is still out on whether Zubsolv works as well as Suboxone. It is the authors’ opinion that Suboxone and Zubsolv should be compared by their dose size and not the claimed bio-availability of the drug. If I had the choice of Suboxone 8mg/2mg v.s. Zubsolv 5.7mg dose I would take Suboxone as it contains more of the medication.
Dosing Comparison For Treatment of Opiate Addiction
Zubsolv’s 5.7 mg Burprenorphine with 1.4 mg Naloxone comes in a round Menthol flavored sublingual tablet, and is said to have a higher bio-availability than Suboxone strips making it equally as effective as Suboxone in the 8mg/2mg size.
Zubsolv’s 1.4 mg Burprenorphine with .36 mg Naloxone comes in a triangular Menthol flavored sublingual tablet, and is said to have a higher bio-availability than Suboxone strips making it equally as effective as Suboxone in the 2mg/.5mg size.
How to take Zubsolv for Opiate Addiction
Taking Zubsolv is similar to taking Suboxone sublingual film, or sublingual tablets. Simply open the package and place the dose under your tongue allowing it to dissolve naturally. Like Suboxone, movement, talking, or drinking while dissolving the tablet is not recommended. Full instructions for taking Zubsolv can be found on Orexo’s Zubsolv website.